Pediatric Bone Marrow Transplant (BMT) in India
- Bone marroww transplantation is a medical procedure used to treat various hematologic conditions in children, including leukemia, lymphoma, and certain genetic disorders.
- The procedure involves replacing damaged or diseased bone marroww with healthy stem cells.
Types of Pediatric BMT
- Autologous transplant .
- Allogeneic transplant .
- Matched sibling donor .
- Matched unrelated donor .
- Haploidentical donor .
- Syngeneic transplant (identical twins)
Indications for Pediatric BMT
- Hematological malignancies (e.g., leukemia, lymphoma) .
- Non-malignant disorders (e.g., thalassemia, sickle cell disease, aplastic anemia) .
- Genetic disorders (e.g., inherited immunodeficiencies)
- mutations in hemoglobin genes.
Donor Selection
- Criteria for selecting donors in pediatric patients .
- Role of donor registries and matching algorithms .
- Growth delays in children
- Ethical considerations in donor selection.
Pre-Transplant Evaluation
- Comprehensive assessment of the pediatric patient.
- Importance of psychosocial evaluations for families .
- Pre-treatment protocols and counseling
The Transplant Procedure
- Conditioning regimen (chemotherapy, radiation)
- Infusion of stem cells and monitoring during the procedure .
- Post-transplant care and management
Complications and Management
- Risks specific to pediatric patients (e.g., growth delays, developmental issues) .
- Management of graft-versus-host disease (GVHD) .
- Long-term follow-up and survivorship issues.
Recent Advances and Research
- Innovations in transplant techniques for children .
- Role of immunotherapy and targeted therapies .
- Continuous examination and clinical preliminaries in pediatric BMT in India
Conclusion
- Pediatric bone marroww transplantation is a complex but potentially life-saving procedure for children with severe hematologic and genetic disorders.
- With advances in medical technology and supportive care, outcomes continue to improve, offering hope for recovery and a better quality of life for young patients.
- Comprehensive care before, during, and after the transplant is essential to address the unique needs of pediatric patients and their families.
- Regular monitoring for late effects of treatment, such as growth issues, organ function, and the risk of secondary cancers.
Departments
Blood Cancer
Sickle Cell Anaemia
Allogeneic Transplant
Haploidentical Transplant
Syngeneic Transplant
Related Hospitals
Indraprastha Apollo Hospitals (Jasola, Delhi)
Max Super Specialty Hospital Gurgaon
Artemis Hospital (Gurgaon)
Jaypee Hospital Noida Delhi NCR India
