Thalassemia in India
- A hereditary blood issue portrayed by diminished hemoglobin creation.
Types of Thalassemia
- Alpha Thalassemia
- Beta Thalassemia
Causes and Risk Factors
1.Genetic Factors:
- Inherited mutations in hemoglobin genes.
2. Prevalence in India:
- Higher rates in certain regions and ethnic groups (e.g., Mediterranean, Southeast Asian communities).
- Radiation and certain medications.
Symptoms
1. Common Symptoms:
- Fatigue and weakness.
- Pale skin and jaundice.
- Growth delays in children.
- Bone deformities (e.g., facial changes).
Diagnosis
1. Physical Examination:
- Assessment of signs and symptoms.
3. Blood Tests:
- Complete blood count (CBC) and hemoglobin electrophoresis.
2. Genetic Testing:
- Identification of specific mutations responsible for thalassemia.
Treatment Options
1. Regular Blood Transfusions:
- Management of anemia and prevention of complications.
2. Iron Chelation Therapy:
- Removal of excess iron from the body due to frequent transfusions.
3. Bone Marrow/Stem Cell Transplant:
- Potentially curative option for eligible patients.
4. Medications:
- Treatments to stimulate hemoglobin production (e.g., hydroxyurea).
Prognosis
1.Factors Influencing Prognosis :
- Type of thalassemia, age at diagnosis, and adherence to treatment.
2. Life Expectancy
- improved with headways in treatment and the board methodologies.
Recent Advances in Research
1. Gene Therapy:
- Ongoing research into curative gene therapies..
2. Innovative Treatments:
- Development of new medications and supportive care strategies.
Conclusion
1. Summary of Thalassemia Importance:
- Emphasis on the need for early diagnosis and comprehensive management.
2. Encouragement for Awareness:
- Importance of awareness programs for screening and prevention.
Departments
Blood Cancer
Sickle cell Anaemia
Allogeneic Transplant
Haploidentical Transplant
Syngeneic Transplant
Related Hospitals
Indraprastha Apollo Hospitals (Jasola, Delhi)
Max Super Specialty Hospital Gurgaon
Artemis Hospital (Gurgaon)
Jaypee Hospital Noida Delhi NCR India
Narayana Superspecialty Hospital Gurgaon
W Pratiksha Hospital (Gurgaon)
